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Research suggests acupuncture may improve insulin sensitivity through effects on the nervous system and on signaling pathways in muscle and fat tissue. A 2023 meta-analysis published in Heliyon found that acupuncture was associated with greater reductions in a standard insulin resistance marker (HOMA-IR) compared to other treatments across 17 trials. Evidence is still developing, and individual responses vary, but insulin sensitivity is one of the better-supported areas of acupuncture research in PCOS.