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Yes – lower back pain is one of the most well-researched applications in acupuncture, with support from Cochrane reviews, the American College of Physicians clinical guidelines, and the CDC's non-pharmacological pain management recommendations. Multiple large-scale trials have found that acupuncture produces significantly greater pain reduction and functional improvement than sham acupuncture or usual care alone. It is recommended as a first-line non-pharmacological treatment for chronic lower back pain.