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Research suggests it can. A 2024 randomized trial published in JAMA Internal Medicine found that people with disc-related sciatica who received a course of acupuncture experienced roughly twice the reduction in leg pain compared to those receiving a sham procedure — and those benefits held for the full 52 weeks of the study. As with any treatment, individual results vary, and acupuncture tends to work best as part of a broader care plan rather than a standalone fix.